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Iodine-131 S values for use in organ dose estimation of Korean patients in radioiodine therapy
Nuclear Engineering and Technology ( IF 2.6 ) Pub Date : 2021-09-06 , DOI: 10.1016/j.net.2021.08.027
Yeon Soo Yeom 1, 2 , Bangho Shin 3 , Chansoo Choi 3 , Haegin Han 3 , Chan Hyeong Kim 3
Affiliation  

In the present study, iodine-131 S values (rT ← thyroid) were calculated for 30 target organs and tissues using the most recently developed Korean reference computational phantoms. The calculated S values were then compared with those of the International Commission on Radiological Protection (ICRP) reference computational phantoms to investigate the dosimetric impact of the Korean S values against those of the ICRP reference phantoms. The results showed significant differences in the S values due to the different anatomical/morphological characteristics between the Korean and ICRP reference phantoms. Most target organs/tissues showed that the S values of the Korean reference phantoms are lower than those of the ICRP reference phantoms, by up to about 4 times (male spleen and female thymus). Exceptionally, three target organs/tissues (gonads, thyroid, and extrathoracic region) showed that the S values of the Korean reference phantoms are greater, by 1.5–3.7 times. We expect that the S values calculated in the present study will be beneficially used to estimate organ/tissue doses of Korean patients under radioiodine therapy.



中文翻译:

Iodine-131 S 值用于韩国放射碘治疗患者器官剂量估计

在本研究中,碘 131 S 值 (r T← 甲状腺)使用最新开发的韩国参考计算模型计算了 30 个目标器官和组织。然后将计算出的 S 值与国际放射防护委员会 (ICRP) 参考计算体模的值进行比较,以研究韩国 S 值与 ICRP 参考体模的剂量学影响。结果显示,由于韩国和 ICRP 参考体模之间的解剖学/形态学特征不同,S 值存在显着差异。大多数目标器官/组织显示,韩国参考体模的 S 值低于 ICRP 参考体模的 S 值,最多约 4 倍(男性脾脏和女性胸腺)。特殊情况下,三个靶器官/组织(性腺、甲状腺、和胸外区域)表明,韩国参考体模的 S 值更大,为 1.5-3.7 倍。我们预计本研究中计算的 S 值将有益地用于估计接受放射性碘治疗的韩国患者的器官/组织剂量。

更新日期:2021-09-06
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