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The impact of the American Heart Association guidelines on patients treated for incomplete Kawasaki disease
Cardiology in the Young ( IF 0.9 ) Pub Date : 2021-09-06 , DOI: 10.1017/s1047951121003632
Megan M Blaney 1 , Richard V Williams 2 , Igor A Areinamo 3 , Michael Sauer 1 , Lloyd Y Tani 2 , Zhining Ou 2 , L LuAnn Minich 2 , Dongngan T Truong 2
Affiliation  

Objectives:

To compare patients treated for incomplete Kawasaki disease whose practitioners followed versus did not follow American Heart Association criteria and to evaluate the association of cardiology consultation with adherence to these guidelines.

Study design:

Single centre retrospective cohort study of patients <18 years old who received ≥1 dose of intravenous immunoglobulin for Kawasaki disease between 01/2006 and 01/2018. We collected demographics, clinical and laboratory data, coronary artery abnormalities, and cardiology consultation status. Patients treated for incomplete Kawasaki disease were divided into two groups based on adherence versus nonadherence to American Heart Association guidelines and compared by Wilcoxon rank sum test and chi-squared or Fisher’s exact test.

Results:

Of the 357 patients treated for Kawasaki disease, 109 (31%) were classified as incomplete Kawasaki disease. The American Heart Association algorithm for identifying patients with incomplete Kawasaki disease was followed in 81/109 (74%). Coronary artery abnormalities were present in 46/109 (42%) of the patients who were treated for incomplete Kawasaki disease. Cardiology consultation was more frequent in those fulfilling American Heart Association criteria for the diagnosis of incomplete Kawasaki disease versus those who did not fulfill criteria (76% versus 48%, p = 0.005).

Conclusions:

Over 25% of patients treated for incomplete Kawasaki disease did not meet American Heart Association guidelines. Guidelines were more frequently followed when the paediatric cardiology team was consulted. Consulting physicians with experience and expertise in the evaluation and management of incomplete KD should be strongly considered in the care of these patients.



中文翻译:

美国心脏协会指南对治疗不完全川崎病患者的影响

目标:

比较接受不完全川崎病治疗的患者,其从业者遵循与不遵循美国心脏协会标准,并评估心脏病咨询与遵守这些指南的关联。

学习规划:

2006 年 1 月至 2018 年 1 月期间接受 ≥1 剂静脉注射免疫球蛋白治疗川崎病患者的单中心回顾性队列研究。我们收集了人口统计学、临床和实验室数据、冠状动脉异常和心脏病咨询状态。接受不完全川崎病治疗的患者根据对美国心脏协会指南的依从性与不依从性分为两组,并通过 Wilcoxon 秩和检验和卡方或 Fisher 精确检验进行比较。

结果:

在接受川崎病治疗的 357 名患者中,109 名(31%)被归类为不完全性川崎病。81/109 (74%) 遵循美国心脏协会用于识别不完全川崎病患者的算法。接受不完全川崎病治疗的患者中有 46/109 (42%) 存在冠状动脉异常。与不符合标准的患者相比,符合美国心脏协会诊断不完全川崎病标准的患者更频繁地咨询心脏病学(76% 对 48%,p = 0.005)。

结论:

超过 25% 接受不完全川崎病治疗的患者不符合美国心脏协会的指南。当咨询儿科心脏病学团队时,更频繁地遵循指南。在治疗这些患者时,应强烈考虑咨询在评估和管理不完全 KD 方面具有经验和专业知识的医生。

更新日期:2021-09-06
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