Gold and Selenium ions have been incorporated into hydroxyapatite (HAP) using the co-precipitation technique at different contributions of Au(III). The obtained compositions were inspected via X-ray diffraction (XRD), Fourier transforms infrared (FTIR), and field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM). Structural parameters showed that Au content has a noticeable role in altering HAP lattice. TEM images display that the grain width decreased from 30 nm in 0.0Au/Se-HAP to 15 nm in 0.8Au/Se-HAP. The c/a ratio denoted a slight distortion in lattice after Au(III) contribution. Moreover, the roughness average increased from 26.3 nm reaching 32.4 nm for the lowest and the highest additional Au(III) contents. The compositions of 0.4Au/Se-HAP and 0.6Au/Se-HAP showed low crystallinity with surface defects, subsequently the highest percentage in cell viability. Furthermore, the indirect bandgaps become narrow with increasing additional Au(III) contribution starting from 6.45 to 6.40 eV. The refractive index shows a decreasing trend from 1.61 to 1.59 with increasing the Au(III) content. Cell viability starts from 94.0 ± 5% in 0.0Au/Se-HAP composition and increases gradually to more than 98.2 ± 4% for 0.6Au/Se-HAP. This work might boost more exploration of Au/Se-HAP as a promising material for biomedical utilizations.

金和硒离子已使用共沉淀技术以不同的 Au(III) 贡献合并到羟基磷灰石 (HAP) 中。通过 X 射线衍射 (XRD)、傅里叶变换红外 (FTIR) 和场发射扫描电子显微镜 (FESEM)、透射电子显微镜 (TEM) 对获得的组合物进行检查。结构参数表明，Au 含量在改变 HAP 晶格方面具有显着作用。TEM 图像显示晶粒宽度从 0.0Au/Se-HAP 中的 30 nm 减小到 0.8Au/Se-HAP 中的 15 nm。c/a 比率表示在 Au(III) 贡献后晶格的轻微畸变。此外，对于最低和最高附加金（III）含量，粗糙度平均值从 26.3 nm 增加到 32.4 nm。0.4Au/Se-HAP 和 0.6Au/Se-HAP 的组成表现出低结晶度和表面缺陷，随后细胞活力的最高百分比。此外，间接带隙随着从 6.45 到 6.40 eV 的额外 Au(III) 贡献的增加而变窄。随着 Au(III) 含量的增加，折射率显示出从 1.61 到 1.59 的下降趋势。细胞活力从 0.0Au/Se-HAP 组成的 94.0 ± 5% 开始，逐渐增加到 0.6Au/Se-HAP 的 98.2 ± 4% 以上。这项工作可能会促进对 Au/Se-HAP 作为一种有前途的生物医学利用材料的更多探索。0Au/Se-HAP 组成并逐渐增加到 0.6Au/Se-HAP 的 98.2 ± 4% 以上。这项工作可能会促进对 Au/Se-HAP 作为一种有前途的生物医学利用材料的更多探索。0Au/Se-HAP 组成并逐渐增加到 0.6Au/Se-HAP 的 98.2 ± 4% 以上。这项工作可能会促进对 Au/Se-HAP 作为一种有前途的生物医学利用材料的更多探索。