Omics in the detection and identification of biosynthetic pathways related to mycotoxin synthesis,Analytical Methods

当前位置： X-MOL 学术 › Anal. Methods › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Omics in the detection and identification of biosynthetic pathways related to mycotoxin synthesis
Analytical Methods ( IF 2.7 ) Pub Date : 2021-08-25 , DOI: 10.1039/d1ay01017d
Nicolás Mateo González-López ₁ , Kevin Andrey Huertas-Ortiz ₁ , John Emerson Leguizamon-Guerrero ₂ , María Mercedes Arias-Cortés ₂ , Claudia Patricia Tere-Peña ₂ , Javier Eduardo García-Castañeda ₁ , Zuly Jenny Rivera-Monroy ₁

Affiliation

Mycotoxins are secondary metabolites that are known to be toxic to humans and animals. On the other hand, some mycotoxins and their analogues possess antioxidant as well as antitumor properties, which could be relevant in the fields of pharmaceutical analysis and food research. Omics techniques are a group of analytical tools applied in the biological sciences in order to study genes (genomics), mRNA (transcriptomics), proteins (proteomics), and metabolites (metabolomics). Omics have become a vital tool in the field of mycotoxins, especially contributing to the identification of biomarkers with potential use for the detection of mycotoxigenic species and the gathering of information about the biosynthetic pathways of mycotoxins in different environments. This approach has provided tools for the development of prevention strategies and control measures for different mycotoxins. Additionally, research has revealed important information about the impact of global warming and climate change on the prevalence of mycotoxin issues in society. In the context of foodomics, the aim is to apply omics techniques in order to ensure food safety. The objective of the present review is to determine the state of the art regarding the development of analytical techniques based on omics in the identification of biosynthetic pathways related to mycotoxin synthesis.

中文翻译：

检测和鉴定与霉菌毒素合成相关的生物合成途径的组学

霉菌毒素是已知对人类和动物有毒的次级代谢物。另一方面，一些真菌毒素及其类似物具有抗氧化和抗肿瘤特性，这可能与药物分析和食品研究领域相关。组学技术是一组应用于生物科学的分析工具，用于研究基因（基因组学）、mRNA（转录组学）、蛋白质（蛋白质组学）和代谢物（代谢组学）。组学已成为真菌毒素领域的重要工具，尤其有助于鉴定具有潜在用途的生物标志物，用于检测产生霉菌毒素的物种和收集有关不同环境中霉菌毒素生物合成途径的信息。这种方法为制定不同真菌毒素的预防策略和控制措施提供了工具。此外，研究还揭示了有关全球变暖和气候变化对社会霉菌毒素问题流行影响的重要信息。在食品组学的背景下，目的是应用组学技术以确保食品安全。本综述的目的是确定基于组学的分析技术在鉴定与霉菌毒素合成相关的生物合成途径方面的发展现状。目的是应用组学技术以确保食品安全。本综述的目的是确定基于组学的分析技术在鉴定与霉菌毒素合成相关的生物合成途径方面的发展现状。目的是应用组学技术以确保食品安全。本综述的目的是确定基于组学的分析技术在鉴定与霉菌毒素合成相关的生物合成途径方面的发展现状。

更新日期：2021-09-06

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11