When Supramolecular Chemistry Meets Chemical Biology: New Strategies to Target Proteins through Host-Guest Interactions,ChemBioChem

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When Supramolecular Chemistry Meets Chemical Biology: New Strategies to Target Proteins through Host-Guest Interactions
ChemBioChem ( IF 2.6 ) Pub Date : 2021-09-06 , DOI: 10.1002/cbic.202100357
Wenbing Cao _{1,

2} , Xuewen Qin ₁ , Tao Liu ₁

Affiliation

Protein targeting through host-guest recognition is an exciting area but is limited by the lack of specific recognition element on protein. Chemical biology methods for site-specific protein modification provide powerful tools for introducing guest molecules into proteins and will greatly expand the scope of protein targeting using supramolecular chemistry.

中文翻译：

当超分子化学遇到化学生物学：通过主客体相互作用靶向蛋白质的新策略

通过主客体识别进行蛋白质靶向是一个令人兴奋的领域，但由于蛋白质上缺乏特异性识别元件而受到限制。用于位点特异性蛋白质修饰的化学生物学方法为将客体分子引入蛋白质提供了强大的工具，并将极大地扩展使用超分子化学的蛋白质靶向范围。

更新日期：2021-10-13

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