SARS-CoV-2 sculpts the immune system to induce sustained virus-specific naïve-like and memory B-cell responses,Clinical & Translational Immunology

当前位置： X-MOL 学术 › Clin. Transl. Immunol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

SARS-CoV-2 sculpts the immune system to induce sustained virus-specific naïve-like and memory B-cell responses
Clinical & Translational Immunology ( IF 4.6 ) Pub Date : 2021-09-05 , DOI: 10.1002/cti2.1339
Leire de Campos-Mata ₁ , Sonia Tejedor Vaquero ₁ , Roser Tachó-Piñot ₁ , Janet Piñero ₂ , Emilie K Grasset ₃ , Itziar Arrieta Aldea ₄ , Natalia Rodrigo Melero ₅ , Carlo Carolis ₅ , Juan P Horcajada ₄ , Andrea Cerutti _{1,

3,

6} , Judit Villar-García ₄ , Giuliana Magri ₁

Affiliation

SARS-CoV-2 infection induces virus-reactive memory B cells expressing unmutated antibodies, which hints at their emergence from naïve B cells. Yet, the dynamics of virus-specific naïve B cells and their impact on immunity and immunopathology remain unclear.

中文翻译：