In this study, cupric oxide–polyaniline (CuO–PANI) composite was prepared by two-step methodology. First step was involved in the synthesis of PANI by the chemical oxidative polymerization of aniline in the presence of (NH₄)₂S₂O₈ as an oxidizing agent. In the second step, 25 mg of PANI was used as template for making a composite with CuO by hydrothermal method. The crystalline phase, morphology and composition of composite material were investigated by the powder X-ray diffraction and scanning electron microscopy techniques. The composite material contained the monoclinic phase of CuO and some poor diffraction patterns of PANI. The composite material exhibits a flower-like morphology. The CuO–PANI composite was deposited on the glassy carbon electrode and used for the electrochemical determination of hydrochlorothiazide (HCT) in Britton–Robinson (B–R) buffer pH 4.0 by the cyclic voltammetry. The HCT has shown a well resolved anodic peak at 1.20 V against Ag/AgCl reference electrode. The electrode kinetics was diffusion controlled and irreversible in nature. The CuO–PANI composite possessed a linear from 8 to 52 µM HCT concentration with a regression coefficient of 0.99. The limit of detection of the CuO–PANI composite was obtained as 0.8 µM for the HCT. The CuO–PANI composite is highly selective, stable and sensitive for the HCT. Therefore, we believe that the newly prepared CuO–PANI composite material can be useful for the different electrochemical applications.

在这项研究中，氧化铜-聚苯胺（CuO-PANI）复合材料是通过两步法制备的。第一步是在 (NH ₄ ) ₂ S ₂ O ₈存在下通过苯胺的化学氧化聚合合成 PANI作为氧化剂。在第二步中，以 25 mg PANI 为模板，通过水热法制备与 CuO 的复合材料。通过粉末X射线衍射和扫描电镜技术研究了复合材料的晶相、形貌和组成。复合材料含有CuO的单斜相和PANI的一些较差的衍射图。复合材料呈现花状形态。CuO-PANI 复合物沉积在玻璃碳电极上，并用于通过循环伏安法在 Britton-Robinson (B-R) 缓冲液 pH 4.0 中电化学测定氢氯噻嗪 (HCT)。HCT 显示出在 1.20 V 处相对于 Ag/AgCl 参比电极的解析良好的阳极峰。电极动力学是扩散控制的，本质上是不可逆的。CuO-PANI 复合材料具有 8 至 52 µM HCT 浓度的线性，回归系数为 0.99。对于 HCT，CuO-PANI 复合材料的检测限为 0.8 µM。CuO-PANI 复合材料对 HCT 具有高度选择性、稳定性和敏感性。因此，我们相信新制备的 CuO-PANI 复合材料可用于不同的电化学应用。