Within the context of mixture theory, an attempt is made to solve a particular problem of radially directed fluid diffusion through a two-layer thick-walled pre-stressed fibrous hollow cylinder submitted to combined large deformations. With respect to both limitations due to perfect interface hypothesis and particular properties of rubber-fluid mixture, our investigation exhibit new results, which show interesting effects of both arterial stiffness in each layer as well as stretching and torsion upon applied mass flux as a function of pressure difference, but also upon spatial variations of both radial and tangential stretch ratios. These results could easily be echoed as an effective aid to improve the methods of making prosthetic conduits for use with living tissue; and can potentially help in understanding de-stiffening therapy, which is appearing as a potential strategy to decrease the stroke incidence and enhance the functional prognosis.

在混合物理论的背景下，试图解决径向定向流体扩散通过两层厚壁预应力纤维中空圆柱体的特定问题，该圆柱体受到组合大变形。关于完美界面假设和橡胶-流体混合物的特殊性质所造成的限制，我们的研究展示了新的结果，显示了每层中的动脉刚度以及拉伸和扭转对应用质量通量的有趣影响，作为压差，但也取决于径向和切向拉伸比的空间变化。这些结果很容易得到回应，作为改进制造用于活组织的假体导管的方法的有效帮助；并且可以潜在地帮助理解去僵化疗法，