The presence of Candida species in urine may be due to colonization of this species in the bladder, urinary catheter, and perineum. Candida albicans has been the most commonly isolated from urine samples in patients with candiduria. Several virulence factors include adhesion to host cells, secreted extracellular enzymes, phenotype switching, and biofilm formation are contributing to the pathogenicity of C. albicans. ABC genotyping is the method based on the determination of 25s rDNA and C. albicans is divided into four genotypes include A, B, C, and E. We aimed to identify Candida species from pediatrics and evaluate extracellular enzyme activities, phenotype switching, biofilm formation, and genotyping in isolates. Urine samples collected, cultured, and yielded yeasts were identified. Phenotype switching, biofilm formation, enzymatic patterns, and genotyping of 50 isolates of C. albicans were evaluated. The Genotyping pattern was compared with extracellular enzymes, biofilm formation, and phenotype switching pattern. 16.2% of urine cultures were positive for the different Candida species. The most common species was C. albicans, followed by C. glabrata. Out of 50 isolates of C. albicans, 72% and 28% isolates were recognized as genotypes A and C. All isolates were produced extracellular enzymes and biofilm formation. In conclusion, candiduria with high colony counts is still a challenge in Iranian pediatrics. Genotype A was the predominant genotype among C. albicans strains. There is a statistical difference between esterase and genotypes of C and A C. albicans.

尿液中念珠菌属物种的存在可能是由于该物种在膀胱、导尿管和会阴部定植。白色念珠菌最常从念珠菌患者的尿液样本中分离出来。几种毒力因素包括对宿主细胞的粘附、分泌的细胞外酶、表型转换和生物膜形成都有助于白色念珠菌的致病性。ABC基因分型是基于25s rDNA测定的方法，将白色念珠菌分为A、B、C、E四种基因型。我们的目的是鉴定念珠菌来自儿科的物种并评估细胞外酶活性、表型转换、生物膜形成和分离株的基因分型。对收集、培养和产生酵母的尿液样本进行鉴定。评估了 50 株白色念珠菌的表型转换、生物膜形成、酶促模式和基因分型。将基因分型模式与细胞外酶、生物膜形成和表型转换模式进行比较。16.2% 的尿培养对不同的念珠菌属阳性。最常见的物种是白色念珠菌，其次是光滑念珠菌。在 50 株白色念珠菌中、72% 和 28% 的分离株被识别为基因型 A 和 C。所有分离株都产生细胞外酶和生物膜形成。总之，具有高菌落数的念珠菌仍然是伊朗儿科的一个挑战。基因型 A 是白色念珠菌菌株中的主要基因型。白色念珠菌和白色念珠菌的酯酶和基因型之间存在统计学差异。