Regions of the world exposed to Zika-linked microcephaly cases have experienced significant declines in fertility. In urban settings, arboviral outbreaks depend on neighborhood environmental factors including residential land use and density of drainage networks, and tend to be highly localized due to the flight dispersal of the vector mosquito. This study investigates whether fertility decline was significantly higher in neighborhoods containing known Zika cases, compared to unexposed neighborhoods in the city state of Singapore. The results show that the average monthly probability of conception leading to a live birth fell during the Zika epidemic in both exposed and unexposed neighborhoods, and that the decline was not significantly greater in neighborhoods with known cases. The study suggests that the fertility response to perceived infection risks was city-wide rather than localized. Public disclosures of outbreak locations did not lead to a disproportionate response in affected neighborhoods.

世界上暴露于与寨卡病毒相关的小头畸形病例的地区生育率显着下降。在城市环境中，虫媒病毒的爆发取决于社区环境因素，包括住宅用地和排水网络的密度，并且由于媒介蚊子的飞行传播而往往高度局部化。这项研究调查了与新加坡城邦未暴露的社区相比，在已知寨卡病毒病例的社区中，生育率下降是否显着更高。结果表明，在寨卡病毒流行期间，在暴露和未暴露的社区中，导致活产的平均月受孕概率均下降，而在已知病例的社区中，下降幅度并不显着。该研究表明，对感知感染风险的生育反应是全市范围的，而不是局部的。疫情爆发地点的公开披露并未导致受影响社区做出不成比例的反应。