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Impact of dietary compositions and patterns on the prevalence of nonalcoholic fatty liver disease in Japanese men: a cross-sectional study
BMC Gastroenterology ( IF 2.5 ) Pub Date : 2021-09-04 , DOI: 10.1186/s12876-021-01919-x
Chihiro Nakashita 1, 2 , Lu Xi 1 , Yasushi Inoue 1 , Ryota Kabura 1 , Shota Masuda 1 , Yuko Yamano 3 , Takahiko Katoh 1
Affiliation  

This study aimed to examine the impact of dietary compositions and patterns on nonalcoholic fatty liver disease (NAFLD) morbidity in Japanese men. We conducted a cross-sectional study of 281 individuals who underwent comprehensive medical examinations during health screening. Dietary intake was assessed using a semi-quantitative food frequency questionnaire, and factor analysis was performed to detect dietary patterns. NAFLD was diagnosed by the presence of fatty liver on abdominal ultrasonography in nondrinkers (< 30 g/day), and patients were categorized into control (n = 192) and NAFLD groups (n = 89). Compared with the control group, the NAFLD group consumed fewer mushrooms. Three dietary patterns were identified, namely, a healthy pattern, a western pattern, and a snack pattern. The score of healthy pattern was negatively correlated with the risk of NAFLD. Compared with the lowest tertile of the healthy pattern, the middle tertile was associated with a lower risk of NAFLD after adjusting for age, physical activity, and smoking (odds ratio: 0.47, 95% confidence interval: 0.25–0.91). After further adjustments for body mass index, the middle tertile was associated with a lower risk of NAFLD (odds ratio: 0.46, 95% confidence interval: 0.23–0.92). A healthy dietary pattern comprising frequent intake of seaweeds, vegetables, mushrooms, pulses, and potatoes and starches was associated with a lower risk of NAFLD in Japanese men. In our opinion, this healthy pattern closely resembles the Japanese Washoku diet, indicating that adherence to Washoku may help prevent NAFLD.

中文翻译:

饮食成分和模式对日本男性非酒精性脂肪肝患病率的影响:一项横断面研究

本研究旨在检查饮食成分和模式对日本男性非酒精性脂肪性肝病 (NAFLD) 发病率的影响。我们对 281 名在健康筛查期间接受全面体检的人进行了横断面研究。使用半定量食物频率问卷评估膳食摄入量,并进行因子分析以检测膳食模式。NAFLD 通过不饮酒者(< 30 g/天)腹部超声检查发现脂肪肝来诊断,患者被分为对照组(n = 192)和 NAFLD 组(n = 89)。与对照组相比,NAFLD组食用的蘑菇更少。确定了三种饮食模式,即健康模式、西方模式和零食模式。健康模式得分与NAFLD风险呈负相关。与健康模式的最低三分位数相比,在调整年龄、体力活动和吸烟后,中间三分位数与较低的 NAFLD 风险相关(优势比:0.47,95% 置信区间:0.25-0.91)。对体重指数进行进一步调整后,中间三分位数与 NAFLD 的风险较低相关(优势比:0.46,95% 置信区间:0.23–0.92)。包括经常摄入海藻、蔬菜、蘑菇、豆类、土豆和淀粉在内的健康饮食模式与日本男性患 NAFLD 的风险较低有关。我们认为,这种健康模式与日本和食饮食非常相似,表明坚持和食可能有助于预防 NAFLD。与健康模式的最低三分位数相比,在调整年龄、体力活动和吸烟后,中间三分位数与较低的 NAFLD 风险相关(优势比:0.47,95% 置信区间:0.25-0.91)。对体重指数进行进一步调整后,中间三分位数与 NAFLD 的风险较低相关(优势比:0.46,95% 置信区间:0.23–0.92)。包括经常摄入海藻、蔬菜、蘑菇、豆类、土豆和淀粉在内的健康饮食模式与日本男性患 NAFLD 的风险较低有关。我们认为,这种健康模式与日本和食饮食非常相似,表明坚持和食可能有助于预防 NAFLD。与健康模式的最低三分位数相比,在调整年龄、体力活动和吸烟后,中间三分位数与较低的 NAFLD 风险相关(优势比:0.47,95% 置信区间:0.25-0.91)。对体重指数进行进一步调整后,中间三分位数与 NAFLD 的风险较低相关(优势比:0.46,95% 置信区间:0.23–0.92)。包括经常摄入海藻、蔬菜、蘑菇、豆类、土豆和淀粉在内的健康饮食模式与日本男性患 NAFLD 的风险较低有关。我们认为,这种健康模式与日本和食饮食非常相似,表明坚持和食可能有助于预防 NAFLD。0.47,95% 置信区间:0.25–0.91)。对体重指数进行进一步调整后,中间三分位数与 NAFLD 的风险较低相关(优势比:0.46,95% 置信区间:0.23–0.92)。包括经常摄入海藻、蔬菜、蘑菇、豆类、土豆和淀粉在内的健康饮食模式与日本男性患 NAFLD 的风险较低有关。我们认为,这种健康模式与日本和食饮食非常相似,表明坚持和食可能有助于预防 NAFLD。0.47,95% 置信区间:0.25–0.91)。对体重指数进行进一步调整后,中间三分位数与 NAFLD 的风险较低相关(优势比:0.46,95% 置信区间:0.23–0.92)。包括经常摄入海藻、蔬菜、蘑菇、豆类、土豆和淀粉在内的健康饮食模式与日本男性患 NAFLD 的风险较低有关。我们认为,这种健康模式与日本和食饮食非常相似,表明坚持和食可能有助于预防 NAFLD。土豆和淀粉与日本男性患 NAFLD 的风险较低有关。我们认为,这种健康模式与日本和食饮食非常相似,表明坚持和食可能有助于预防 NAFLD。土豆和淀粉与日本男性患 NAFLD 的风险较低有关。我们认为,这种健康模式与日本和食饮食非常相似,表明坚持和食可能有助于预防 NAFLD。
更新日期:2021-09-04
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