Given the crucial association of hydrogen peroxide with a wide range of human diseases, this compound has currently earned the reputation of being a popular biomolecular target. Although various analytical methods have attracted our attention, fluorescent probes have been used as prominent tools to determine H2O2 to reflect the physiological and pathological conditions of biological systems. The sensitive responsive part of these probes is the boronate ester and boronic acid groups, which are important reporters for H2O2 recognition. In this review, we summarize boronate ester/boronic acid group-based fluorescent probes for H2O2 reported from 2012 to 2020, and we have generally classified the fluorophores into six categories to exhaustively elaborate the design strategy and comprehensive systematic performance. We hope that this review will inspire the exploration of new fluorescent probes based on boronate ester/boronic acid groups for the detection of H2O2 and other relevant analytes.

中文翻译：

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基于硼酸盐的荧光探针作为 H2O2 传感和识别的重要工具。

鉴于过氧化氢与多种人类疾病的关键关联，这种化合物目前已赢得了成为流行生物分子靶标的声誉。尽管各种分析方法引起了我们的注意，但荧光探针已被用作确定 H2O2 以反映生物系统的生理和病理状况的重要工具。这些探针的敏感响应部分是硼酸酯和硼酸基团，它们是 H2O2 识别的重要报告分子。在这篇综述中，我们总结了 2012 年至 2020 年报道的基于硼酸酯/硼酸基团的 H2O2 荧光探针，我们将荧光团大致分为六类，以详尽阐述设计策略和综合系统性能。