Many enhancers exist as clusters in the genome, which has led to the coining of the term ‘super-enhancer’. In this Viewpoint, five experts discuss our biological understanding of enhancer clusters, how we can responsibly study their functions, and their opinions on whether names for enhancer clusters are an informative reflection of their functional properties. They also provide their thoughts on key unanswered questions and future directions in the field. In this Viewpoint, five experts discuss our biological understanding of super-enhancers, how we can responsibly study their functions, and their opinions on whether names for enhancer clusters are an informative reflection of their functional properties.

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测试超级增强子概念

许多增强子在基因组中以簇的形式存在，这导致了“超级增强子”一词的诞生。在这个观点中，五位专家讨论了我们对增强子簇的生物学理解，我们如何负责任地研究它们的功能，以及他们对增强子簇的名称是否能反映其功能特性的看法。他们还提供了对该领域未解决的关键问题和未来方向的看法。在本观点中，五位专家讨论了我们对超级增强子的生物学理解，我们如何负责任地研究它们的功能，以及他们对增强子簇的名称是否能反映其功能特性的看法。