Postoperative atrial fibrillation (POAF) is the most common cardiac dysrhythmia to occur after coronary artery bypass grafting (CABG). However, the risk factors for new-onset POAF after CABG during the perioperative period have yet to be clearly defined. Accordingly, the aim of our systematic review was to evaluate the perioperative predictors of new-onset POAF after isolated CABG. Our review methods adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. We searched seven electronic databases (PubMed, Embase, CINAHL, PsycArticles, Cochrane, Web of Science, and SCOPUS) to identify all relevant English articles published up to January 2020. Identified studies were screened independently by two researchers for selection, according to predefined criteria. The Newcastle–Ottawa Scale was used to evaluate the quality of studies retained. After screening, nine studies were retained for analysis, including 4798 patients, of whom 1555 (32.4%) experienced new-onset POAF after CABG. The incidence rate of new-onset POAF ranged between 17.3% and 47.4%. The following risk factors were identified: old age (p < 0.001), a high preoperative serum creatinine level (p = 0.001), a low preoperative hemoglobin level (p = 0.007), a low left ventricle ejection fraction in Asian patients (p = 0.001), essential hypertension (p < 0.001), chronic obstructive pulmonary disease (p = 0.010), renal failure (p = 0.009), cardiopulmonary bypass use (p = 0.002), perfusion time (p = 0.017), postoperative use of inotropes (p < 0.001), postoperative renal failure (p = 0.001), and re-operation (p = 0.005). All studies included in the analysis were of good quality. The risk factors identified in our review could be used to improve monitoring of at-risk patients for early detection and treatment of new-onset POAF after CABG, reducing the risk of other complications and negative clinical outcomes.

中文翻译：

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冠状动脉旁路移植术后新发术后房颤的围手术期危险因素：系统评价

术后心房颤动 (POAF) 是冠状动脉旁路移植术 (CABG) 后最常见的心律失常。然而，围手术期 CABG 后新发 POAF 的危险因素尚未明确。因此，我们系统评价的目的是评估孤立 CABG 后新发 POAF 的围手术期预测因素。我们的审查方法遵循系统审查和元分析的首选报告项目指南。我们检索了 7 个电子数据库（PubMed、Embase、CINAHL、PsycArticles、Cochrane、Web of Science 和 SCOPUS），以确定截至 2020 年 1 月发表的所有相关英文文章。确定的研究由两名研究人员根据预定义的标准独立筛选以供选择. 纽卡斯尔-渥太华量表用于评估保留研究的质量。筛选后，保留 9 项研究进行分析，包括 4798 名患者，其中 1555 名（32.4%）在 CABG 后出现新发 POAF。新发 POAF 的发生率介于 17.3% 和 47.4% 之间。确定了以下风险因素：高龄 (p < 0.001)、术前血清肌酐水平高 (p = 0.001)、术前血红蛋白水平低 (p = 0.007)、亚洲患者左心室射血分数低 (p = 0.001)、原发性高血压 (p < 0.001)、慢性阻塞性肺疾病 (p = 0.010)、肾功能衰竭 (p = 0.009)、体外循环使用 (p = 0.002)、灌注时间 (p = 0.017)、术后使用正性肌力药(p < 0.001)、术后肾功能衰竭 (p = 0.001) 和再次手术 (p = 0.005)。纳入分析的所有研究质量良好。我们审查中确定的风险因素可用于改善对高危患者的监测，以便在 CABG 后及早发现和治疗新发 POAF，降低其他并发症和负面临床结果的风险。