Phenotyping heart failure patients for iron deficiency and use of intravenous iron therapy: data from the Swedish Heart Failure Registry,European Journal of Heart Failure

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Phenotyping heart failure patients for iron deficiency and use of intravenous iron therapy: data from the Swedish Heart Failure Registry
European Journal of Heart Failure ( IF 16.9 ) Pub Date : 2021-09-03 , DOI: 10.1002/ejhf.2338
Peter Moritz Becher _{1,

2,

3} , Benedikt Schrage _{1,

2,

3} , Lina Benson ₁ , Marat Fudim _{4,

5} , Carin Corovic Cabrera _{6,

7} , Ulf Dahlström ₈ , Giuseppe M C Rosano _{9,

10} , Ewa A Jankowska ₁₁ , Stefan D Anker ₁₂ , Lars H Lund _{1,

13} , Gianluigi Savarese _{1,

13}

Affiliation

Division of Cardiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Department of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
German Center of Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Berlin, Germany.
Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Duke Clinical Research Institute, Durham, NC, USA.
Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.
Department of Cardiology, Södersjukhuset, Stockholm, Sweden.
Department of Cardiology and Department of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden.
St George's Hospital Medical School, London, UK.
IRCCS San Raffaele Roma, Rome, Italy.
Department of Heart Diseases, Wroclaw Medical University, and Centre for Heart Diseases, University Hospital, Wroclaw, Poland.
Department of Cardiology (CVK); and Berlin Institute of Health Center for Regenerative Therapies (BCRT); German Centre for Cardiovascular Research (DZHK) partner site Berlin; Charité Universitätsmedizin Berlin, Berlin, Germany.
Heart and Vascular Theme, Karolinska University Hospital, Stockholm, Sweden.

Iron deficiency (ID) is associated with poor prognosis regardless of anaemia. Intravenous iron improves quality of life and outcomes in patients with ID and heart failure (HF) with reduced ejection fraction (HFrEF). In the Swedish HF registry, we assessed (i) frequency and predictors of ID testing; (ii) prevalence and outcomes of ID with/without anaemia; (iii) use of ferric carboxymaltose (FCM) and its predictors in patients with ID.

中文翻译：

对缺铁性心力衰竭患者进行表型分析和静脉铁剂治疗的使用：来自瑞典心力衰竭登记处的数据

无论贫血如何，缺铁 (ID) 都与预后不良有关。静脉补铁可改善 ID 和心力衰竭 (HF) 伴射血分数降低 (HFrEF) 患者的生活质量和预后。在瑞典 HF 登记处，我们评估了 (i) ID 测试的频率和预测因素；(ii) 伴有/不伴有贫血的 ID 的患病率和结果；(iii) 在 ID 患者中使用羧基麦芽糖铁 (FCM) 及其预测因子。

更新日期：2021-09-03

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