Dynamic Metabolic Risk Profiling of World Trade Center Lung Disease: A Longitudinal Cohort Study.,American Journal of Respiratory and Critical Care Medicine

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Dynamic Metabolic Risk Profiling of World Trade Center Lung Disease: A Longitudinal Cohort Study.
American Journal of Respiratory and Critical Care Medicine ( IF 19.3 ) Pub Date : 2021-11-01 , DOI: 10.1164/rccm.202006-2617oc
Sophia Kwon ₁ , Myeonggyun Lee ₂ , George Crowley ₁ , Theresa Schwartz ₃ , Rachel Zeig-Owens _{3,

4} , David J Prezant _{3,

5} , Mengling Liu _{2,

6} , Anna Nolan _{1,

3,

6}

Affiliation

Rationale: Metabolic syndrome (MetSyn) increases the risk of World Trade Center (WTC) lung injury (LI). However, the temporal relationship of MetSyn, exposure intensity, and lung dysfunction is not well understood. Objective: To model the association of longitudinal MetSyn characteristics with WTC lung disease to define modifiable risk. Methods: Firefighters, for whom consent was obtained (N = 5,738), were active duty on September 11, 2001 (9/11). WTC-LI (n = 1,475; FEV1% predicted

中文翻译：

世界贸易中心肺部疾病的动态代谢风险分析：一项纵向队列研究。

理由：代谢综合征 (MetSyn) 会增加世贸中心 (WTC) 肺损伤 (LI) 的风险。然而，MetSyn、暴露强度和肺功能障碍的时间关系尚不清楚。目的：模拟纵向 MetSyn 特征与 WTC 肺部疾病的关联，以定义可改变的风险。方法：获得同意的消防员 (N = 5,738) 于 2001 年 9 月 11 日 (9/11) 现役。WTC-LI（n = 1,475；FEV1% 预测

更新日期：2021-09-02

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