This study compared the acute and chronic impact of citrulline malate (CM) supplementation on muscle contractile properties and fatigue rate of the quadriceps. Eighteen recreationally trained males consumed both a placebo (PL) and CM treatment for two separate dosing periods. The first experimental testing session for each dosing period was considered the baseline day, the second session the acute day, and the third session the chronic day, which followed seven consecutive days of supplementation. All testing sessions included exercising on a cycle ergometer at 50%–60% of their max power output for 30 min followed by performing the Thorstensson test on an isokinetic dynamometer. A two-way (Supplement × Time) analysis of variance with repeated measures resulted in no significant interactions (p > .05) (PL: baseline day, acute day, chronic day vs. CM: baseline day, acute day, chronic day) for peak power (in watts) (469 ± 81, 490 ± 97, 502 ± 99 vs. 464 ± 85, 480 ± 103, 501 ± 81); peak torque (in newton meters) (150 ± 26, 157 ± 32, 161 ± 31 vs. 149 ± 27, 156 ± 33, 161 ± 26); fatigue rate (in percentage) (57 ± 9, 57 ± 10, 58 ± 9 vs. 57 ± 10, 56 ± 9, 58 ± 9); and heart rate (in beats per minute) (156 ± 17, 146 ± 13, 146 ± 9 vs. 155 ± 11, 146 ± 11, 146 ± 9). The results of this study suggest that neither acute nor chronic supplementation of CM had an effect on recovery or fatigue rate of the quadriceps.

本研究比较了瓜氨酸苹果酸 (CM) 补充剂对股四头肌肌肉收缩特性和疲劳率的急性和慢性影响。十八名接受过娱乐训练的男性在两个不同的给药期同时服用安慰剂 (PL) 和 CM 治疗。每个给药期的第一个实验测试时段被认为是基线日，第二个时段被认为是急性日，第三个时段被认为是慢性日，随后是连续 7 天的补充。所有测试课程包括在自行车测力计上以最大功率输出的 50%–60% 锻炼 30 分钟，然后在等速测力计上进行 Thorstensson 测试。重复测量的双向（补充×时间）方差分析导致没有显着的交互作用（p > .05)（PL：基线天、急性天、慢性天 vs. CM：基线天、急性天、慢性天）峰值功率（以瓦特为单位）（469 ± 81、490 ± 97、502 ± 99 对 464 ± 85、480 ± 103、501 ± 81)；峰值扭矩（以牛顿米为单位）（150 ± 26、157 ± 32、161 ± 31 对 149 ± 27、156 ± 33、161 ± 26）；疲劳率（百分比）（57 ± 9、57 ± 10、58 ± 9 对 57 ± 10、56 ± 9、58 ± 9）；和心率（每分钟跳动数）（156 ± 17、146 ± 13、146 ± 9 对 155 ± 11、146 ± 11、146 ± 9）。这项研究的结果表明，急性或慢性补充 CM 对股四头肌的恢复或疲劳率均无影响。