Conidia of Trichoderma guizhouense (Hypocreales, Ascomycota) are frequently applied to the production of biofertilizers and biocontrol agents. Conidiation of some Trichoderma species depends on blue light and the action of different blue light receptors. However, the interplay between different blue-light receptors in light signalling remained elusive. Here, we studied the functions of the blue light receptors BLR1 and ENV1, and the MAP kinase HOG1 in blue light signalling in T. guizhouense. We found that the BLR1 dominates light responses and ENV1 is responsible for photoadaptation. Genome-wide gene expression analyses revealed that 1615 genes, accounting for ~13.4% of the genes annotated in the genome, are blue-light regulated in T. guizhouense, and remarkably, these differentially expressed genes (DEGs) including 61 transcription factors. BLR1 and HOG1 are the core components of the light signalling network, which control 79.9% and 73.9% of the DEGs respectively. In addition, the strict regulation of hydrophobin production by the blue light signalling network is impressive. Our study unravels the regulatory network based on the blue light receptors and the MAPK HOG pathway for conidiation, hydrophobin production and other processes in T. guizhouense.

中文翻译：

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贵州木霉蓝光调控分生孢子和疏水蛋白产生调控网络的综合分析

贵州木霉的分生孢子（Hypocreales，Ascomycota）常用于生物肥料和生物防治剂的生产。某些木霉属物种的分生孢子取决于蓝光和不同蓝光受体的作用。然而，光信号中不同蓝光受体之间的相互作用仍然难以捉摸。在这里，我们研究了蓝光受体 BLR1 和 ENV1 以及 MAP 激酶 HOG1 在T中蓝光信号传导中的功能。贵州话 我们发现 BLR1 主导光响应，而 ENV1 负责光适应。全基因组基因表达分析显示，占基因组中注释基因的约 13.4% 的 1615 个基因在T._ _ 贵州人，值得注意的是，这些差异表达基因（DEGs）包括61个转录因子。BLR1和HOG1是光信号网络的核心组件，分别控制79.9%和73.9%的DEG。此外，蓝光信号网络对疏水蛋白产生的严格监管令人印象深刻。我们的研究揭示了基于蓝光受体和 MAPK HOG 途径的调控网络，用于分生孢子、疏水蛋白产生和其他过程。贵州话