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Whole blood transcriptomics identifies gene expression associated with peanut allergy in infants at high risk
Clinical & Experimental Allergy ( IF 6.3 ) Pub Date : 2021-09-02 , DOI: 10.1111/cea.14008 Ashley L Devonshire 1, 2, 3, 4 , Hanli Fan 5 , Mario Pujato 6 , Aditi Paranjpe 6 , Demirkan Gursel 5 , Matthew Schipma 7 , Julia M Dunn 3 , Sandra Andorf 3, 4, 6 , Jacqueline A Pongracic 1, 2 , Leah C Kottyan 3, 4, 8 , Rajesh Kumar 1, 2
中文翻译:
全血转录组学鉴定与高危婴儿花生过敏相关的基因表达
更新日期:2021-09-29
Clinical & Experimental Allergy ( IF 6.3 ) Pub Date : 2021-09-02 , DOI: 10.1111/cea.14008 Ashley L Devonshire 1, 2, 3, 4 , Hanli Fan 5 , Mario Pujato 6 , Aditi Paranjpe 6 , Demirkan Gursel 5 , Matthew Schipma 7 , Julia M Dunn 3 , Sandra Andorf 3, 4, 6 , Jacqueline A Pongracic 1, 2 , Leah C Kottyan 3, 4, 8 , Rajesh Kumar 1, 2
Affiliation
Key Messages
- Gene expression in whole peripheral blood differed between peanut sensitized, allergic and non-allergic, non-sensitized subjects.
- The use of whole blood to examine gene expression differences has limitations.
- Future studies are required for the discovery of novel biomarkers for food allergy.
中文翻译:
全血转录组学鉴定与高危婴儿花生过敏相关的基因表达
关键信息
- 全外周血中的基因表达在花生致敏、过敏和非过敏、非致敏受试者之间存在差异。
- 使用全血检查基因表达差异有局限性。
- 未来的研究需要发现新的食物过敏生物标志物。