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Dissecting melanocytes to predict melanoma
Nature Cell Biology ( IF 17.3 ) Pub Date : 2021-09-02 , DOI: 10.1038/s41556-021-00748-0 Alicia M McConnell 1, 2 , Leonard I Zon 1, 2, 3
Nature Cell Biology ( IF 17.3 ) Pub Date : 2021-09-02 , DOI: 10.1038/s41556-021-00748-0 Alicia M McConnell 1, 2 , Leonard I Zon 1, 2, 3
Affiliation
With advanced high-throughput technologies, scientists can now use transcriptional signatures to study melanocytes as they become cancer. A new study identifies transcriptional programs at single-cell resolution across platforms and species, which enables prediction of melanoma prognosis and response to immune-checkpoint inhibitor therapy.
中文翻译:
解剖黑色素细胞以预测黑色素瘤
借助先进的高通量技术,科学家现在可以使用转录特征来研究黑素细胞变成癌症的过程。一项新研究确定了跨平台和物种的单细胞分辨率转录程序,这使得能够预测黑色素瘤预后和对免疫检查点抑制剂治疗的反应。
更新日期:2021-09-02
中文翻译:
解剖黑色素细胞以预测黑色素瘤
借助先进的高通量技术,科学家现在可以使用转录特征来研究黑素细胞变成癌症的过程。一项新研究确定了跨平台和物种的单细胞分辨率转录程序,这使得能够预测黑色素瘤预后和对免疫检查点抑制剂治疗的反应。