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Commentary on Unexpected Persistently Increased Intraoperative Parathyroid Hormone Concentrations in a Patient with Primary Hyperparathyroidism
Clinical Chemistry ( IF 7.1 ) Pub Date : 2021-09-01 , DOI: 10.1093/clinchem/hvab087
Lorin M Bachmann 1
Affiliation  

This case emphasizes that symptoms of hyperparathyroidism are frequently nonspecific; therefore, diagnosis of this condition relies on accurate measurement of parathyroid hormone (PTH). The case highlights how changes in PTH concentration are used to evaluate parathyroidectomy response. Changes in PTH are also used to monitor response to calcimimetic drugs, which bind to the calcium sensing receptor and suppress secretion of PTH.

中文翻译:

原发性甲状旁腺功能亢进患者术中甲状旁腺激素浓度意外持续升高的评论

该病例强调甲状旁腺功能亢进的症状通常是非特异性的;因此,这种情况的诊断依赖于甲状旁腺激素 (PTH) 的准确测量。该案例强调了如何使用 PTH 浓度的变化来评估甲状旁腺切除术的反应。PTH 的变化也用于监测对拟钙药物的反应,这些药物与钙敏感受体结合并抑制 PTH 的分泌。
更新日期:2021-09-02
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