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Post-translational modifications of proteins associated with yeast peroxisome membrane: An essential mode of regulatory mechanism
Genes to Cells ( IF 2.1 ) Pub Date : 2021-09-02 , DOI: 10.1111/gtc.12892
Terence Infant 1 , Rachayeeta Deb 1 , Suchetana Ghose 1 , Shirisha Nagotu 1
Affiliation  

Peroxisomes are single membrane-bound organelles important for the optimum functioning of eukaryotic cells. Seminal discoveries in the field of peroxisomes are made using yeast as a model. Several proteins required for the biogenesis and function of peroxisomes are identified to date. As with proteins involved in other major cellular pathways, peroxisomal proteins are also subjected to regulatory post-translational modifications. Identification, characterization and mapping of these modifications to specific amino acid residues on proteins are critical toward understanding their functional significance. Several studies have tried to identify post-translational modifications of peroxisomal proteins and determine their impact on peroxisome structure and function. In this manuscript, we provide an overview of the various post-translational modifications that govern the peroxisome dynamics in yeast.

中文翻译:

与酵母过氧化物酶体膜相关的蛋白质的翻译后修饰:调节机制的基本模式

过氧化物酶体是单膜结合的细胞器,对真核细胞的最佳功能很重要。过氧化物酶体领域的开创性发现是使用酵母作为模型进行的。迄今为止,已鉴定出过氧化物酶体的生物发生和功能所需的几种蛋白质。与参与其他主要细胞途径的蛋白质一样,过氧化物酶体蛋白也受到调节​​性翻译后修饰。这些修饰对蛋白质上特定氨基酸残基的鉴定、表征和定位对于理解它们的功能意义至关重要。一些研究试图确定过氧化物酶体蛋白的翻译后修饰,并确定它们对过氧化物酶体结构和功能的影响。在这份手稿中,
更新日期:2021-11-08
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