Cross-coupling reactions are essential for the synthesis of complex organic molecules. Here, we report a nickel-catalyzed Ullmann cross-coupling of two sp2-hybridized organohalides, featuring high cross-selectivity when the two coupling partners are used in a 1:1 ratio. The high chemoselectivity is governed by the bathocuproine ligand. Moreover, the mild reductive reaction conditions allow that a wide range of functional groups are compatible in this Ullmann cross-coupling.

中文翻译：

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浴铜灵使镍催化的两种 sp2 杂化有机卤化物的选择性乌尔曼交叉偶联

交叉偶联反应对于复杂有机分子的合成至关重要。在这里，我们报告了镍催化的两个 sp2 杂化有机卤化物的 Ullmann 交叉偶联，当两个偶联伙伴以 1:1 的比例使用时，具有高交叉选择性。高化学选择性由浴铜灵配体控制。此外，温和的还原反应条件允许广泛的官能团在这种 Ullmann 交叉偶联中相容。