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Mesoporous molecularly imprinted materials: From preparation to biorecognition and analysis
Trends in Analytical Chemistry ( IF 11.8 ) Pub Date : 2021-09-02 , DOI: 10.1016/j.trac.2021.116426
Guiyuan Zhang , Muhammad Mujahid Ali , Xin Feng , Juntao Zhou , Lianghai Hu

Molecular imprinting technology (MIT) refers to the technique of artificially customized materials with a specific shape, size, and functionalized site-specific recognition capability for specific target molecules. Mesoporous materials have an extremely high specific surface area, regularly ordered pore structure, narrow pore size distribution, and wide range of adjustable pore size, which enable them to adsorb and separate macromolecules that are difficult to complete in many microporous zeolite molecular sieves, and especially play a vital role in the catalytic reactions. Molecularly imprinted mesoporous materials possess specific recognition cavities complementary to the shape, size, and functional groups of the template molecule. It can specifically identify and enrich target analytes and has been widely used in sample preparation and chemical/biosensing. In this review, recent advances in molecularly imprinted mesoporous materials for medicine, environmental, proteomics, chirality, catalysis, and sensing, are comprehensively summarized and discussed.



中文翻译:

介孔分子印迹材料:从制备到生物识别和分析

分子印迹技术(MIT)是指人工定制具有特定形状、尺寸和功能化位点特异性识别能力的特定目标分子的材料的技术。介孔材料具有极高的比表面积、规则有序的孔结构、狭窄的孔径分布和广泛的孔径可调范围,使其能够吸附和分离许多微孔沸石分子筛中难以完成的大分子,特别是在催化反应中起重要作用。分子印迹介孔材料具有与模板分子的形状、大小和官能团互补的特定识别腔。它可以特异性地识别和富集目标分析物,已广泛应用于样品制备和化学/生物传感。在这篇综述中,全面总结和讨论了分子印迹介孔材料在医学、环境、蛋白质组学、手性、催化和传感方面的最新进展。

更新日期:2021-09-15
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