Objective

To evaluate the relationship between the timing of infant cereal introduction between 4 and 6 months of age and growth and dietary intake in later childhood.

Study design

A longitudinal cohort study was conducted among healthy children 0-10 years of age participating in The Applied Research Group for Kids cohort study between June 2008 and August 2019 in Toronto, Canada.

Results

Of 8943 children included, the mean (SD) age of infant cereal introduction was 5.7 (2.1) months. In the primary analysis, children who were introduced to infant cereal at 4 vs 6 months had 0.17 greater body mass index z score (95% CI 0.06-0.28; P = .002) and greater odds of obesity (OR 1.82; 95% CI 1.18-2.80; P = .006) at 10 years of age. In the secondary analysis, children who were introduced to infant cereal at 4 vs 6 months had 0.09 greater height-for-age z score (95% CI 0.04-0.15; P = .002) at 1 year of age, an association that was not observed at 5 or 10 years of age. Children who were introduced to infant cereal at 4 vs 6 months had greater nutrition risk which was primarily determined by a less-favorable eating behavior score at 18 months to 5 years of age (0.18 units higher; 95% CI 0.07-0.29; P = .001).

Conclusions

Introduction of infant cereal at 4 vs 6 months was associated with greater body mass index z score, greater odds of obesity, similar height-for-age z score, and less favorable eating behavior. These findings support recommendations for introducing solid food around 6 months of age.

中文翻译：

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儿童后期引入固体食物、生长和营养风险的时机

客观的

评估 4 至 6 个月大的婴儿谷物引入时间与儿童后期生长和膳食摄入之间的关系。

学习规划

2008 年 6 月至 2019 年 8 月，在加拿大多伦多参加儿童应用研究小组队列研究的 0-10 岁健康儿童进行了纵向队列研究。

结果

在包括的 8943 名儿童中，婴儿谷物引入的平均 (SD) 年龄为 5.7 (2.1) 个月。在初步分析中，在 4 个月和 6 个月时被引入婴儿谷类食品的儿童体重指数 z 评分高 0.17（95% CI 0.06-0.28；P  = .002）和肥胖几率更大（OR 1.82；95% CI 1.18-2.80；P  = .006）在 10 岁时。在次要分析中，在 4 个月和 6 个月时被引入婴儿谷类食品的儿童的年龄别身高 z 评分高 0.09（95% CI 0.04-0.15；P = .002) 在 1 岁时，这种关联在 5 岁或 10 岁时未观察到。在 4 个月和 6 个月时被引入婴儿谷类食品的儿童营养风险更大，这主要取决于 18 个月至 5 岁时的不良饮食行为评分（高 0.18 个单位；95% CI 0.07-0.29；P  = .001)。

结论

在 4 个月和 6 个月时引入婴儿谷类食品与更高的体重指数 z 评分、更大的肥胖几率、相似的年龄别身高 z 评分以及不太有利的饮食行为相关。这些发现支持在 6 个月大时引入固体食物的建议。