In this issue of Cancer Cell, Shiao et al. reveal the counteracting role of bacteria and fungi in antitumoral immune responses to radiation therapy (RT). While bacterial depletion impairs the response, fungal depletion improves efficacy of RT. An interplay between innate and adaptive immunity is implicated and orchestrated by Dectin-1.

中文翻译：

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细菌和真菌：癌症放射治疗免疫反应的抵消调节剂

在本期《癌细胞》中，Shiao 等人。揭示细菌和真菌在放射治疗（RT）的抗肿瘤免疫反应中的抵消作用。虽然细菌清除会损害反应，但真菌清除可提高 RT 的功效。先天免疫和适应性免疫之间的相互作用是由 Dectin-1 牵涉和协调的。