Nuclear receptor HR96 up-regulates cytochrome P450 for insecticide detoxification in Tribolium castaneum,Pest Management Science

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Nuclear receptor HR96 up-regulates cytochrome P450 for insecticide detoxification in Tribolium castaneum
Pest Management Science ( IF 3.8 ) Pub Date : 2021-09-02 , DOI: 10.1002/ps.6626
In-Young Kim ₁ , Byungyoon Choi ₁ , Woo-Ram Park ₁ , Yu-Ji Kim ₁ , Bo-Eun Kim ₁ , Seulgi Mun ₂ , Hueng-Sik Choi ₃ , Don-Kyu Kim ₁

Affiliation

Red flour beetle, Tribolium castaneum (T. castaneum), is a major agricultural pest that causes significant damage to stored grains and products. Although hormone receptor 96 (HR96) is known to be the single ortholog corresponding to mammalian constitutive androstane receptor and pregnane X receptor, the structural features of Tribolium HR96 (TcHR96) and its role in insecticide-mediated transcription control of cytochrome P450 enzyme genes in T. castaneum have not been elucidated yet.

中文翻译：

核受体 HR96 上调细胞色素 P450 用于 Tribolium castaneum 中的杀虫剂解毒

红面甲虫Tribolium castaneum (T. castaneum)是一种主要的农业害虫，会对储存的谷物和产品造成严重损害。尽管已知激素受体 96 (HR96) 是与哺乳动物组成型雄甾烷受体和孕烷 X 受体相对应的单一直系同源物，但Tribolium HR96 (TcHR96)的结构特征及其在杀虫剂介导的Tc细胞色素 P450 酶基因转录控制中的作用. castaneum尚未阐明。

更新日期：2021-09-02

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