Bringing Color to Sugars: The Chemical Assembly of Carbohydrates to BODIPY Dyes,The Chemical Record

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Bringing Color to Sugars: The Chemical Assembly of Carbohydrates to BODIPY Dyes
The Chemical Record ( IF 7.0 ) Pub Date : 2021-09-02 , DOI: 10.1002/tcr.202100190
Ana M Gomez ₁ , J Cristobal Lopez ₁

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The combination of carbohydrates with BODIPY fluorophores gives rise to a family of BODIPY-carbohydrate hybrids or glyco-BODIPYs, which mutually benefit from the encounter. Thus, from the carbohydrates standpoint, glyco-BODIPYs can be regarded as fluorescent glycoconjugate derivatives with application in imaging techniques, whereas from the fluorophore view the BODIPY-carbohydrate hybrids benefit from the biocompatibility, water-solubility, and reduced toxicity, among others, brought about by the sugar moiety. In this Account we have intended to present the collection of available methods for the synthesis of BODIPY-carbohydrate hybrids, with a focus on the chemical transformations on the BODIPY core.

中文翻译：

给糖带来颜色：碳水化合物化学组装成 BODIPY 染料

碳水化合物与 BODIPY 荧光团的组合产生了一个 BODIPY-碳水化合物杂合体或糖-BODIPYs 家族，它们从相遇中受益。因此，从碳水化合物的角度来看，糖-BODIPYs 可以被视为在成像技术中应用的荧光糖缀合物衍生物，而从荧光团的角度来看，BODIPY-碳水化合物杂化物受益于生物相容性、水溶性和降低的毒性等，带来了大约由糖部分。在这个帐户中，我们打算展示合成 BODIPY-碳水化合物杂化物的可用方法的集合，重点是 BODIPY 核心的化学转化。

更新日期：2021-09-02

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