Abstract

The effect of the chemical structure of crosslinking agents on the activity of proteins in hydrogels obtained by the copolymerization of acrylamide, a crosslinking agent, and an unsaturated protein derivative is studied. It is shown that interaction between units of the hydrophobic crosslinking agent which increases with an increase in the length of the aliphatic region between the double bonds of the crosslinking agent leads to an additional “hydrophobic crosslinking” of macromolecules and causes a decrease in the activity of the immobilized protein.

中文翻译：

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水凝胶的结构和固定在其中的蛋白质的活性

摘要

研究了交联剂的化学结构对丙烯酰胺、交联剂和不饱和蛋白质衍生物共聚所得水凝胶中蛋白质活性的影响。结果表明，疏水性交联剂单元之间的相互作用随着交联剂双键之间脂肪族区域长度的增加而增加，导致大分子的额外“疏水性交联”并导致其活性降低。固定的蛋白质。