Typical antineoplastic agent doxorubicin (DOX) contamination is a major environmental concern and its efficient purification remains a daunting challenge so far. This work explored the potential of Fe/Pd-doped graphite carbon nitride (g-C₃N₄@Fe/Pd) for DOX removal from water, involving the removal performance, mechanism, and pathway. Structural characterization of g-C₃N₄@Fe/Pd showed that the metallic Pd clusters are decorated on the surface of uniformly distributed iron nanoparticles (~ 28 nm) on g-C₃N₄. The existence of g-C₃N₄ effectively relieved the agglomeration and overgrowth of iron nanoparticles, the strong coupling effect among the Fe, Pd and N demonstrates the excellent DOX removal performance (k = 0.115 min⁻¹) with versatility under different initial concentrations (30–150 mg/L) and material dosages (0.1–0.4 g/L). Three possible degradation pathways of DOX were proposed, where catalytic saccharide moiety elimination is the primary pathway. Importantly, intermediates exhibit lower toxicity and the final degradation product is efficiently adsorbed by g-C₃N₄@Fe/Pd.

典型的抗肿瘤剂阿霉素 (DOX) 污染是一个主要的环境问题，迄今为止，其有效纯化仍然是一项艰巨的挑战。这项工作探索了 Fe/Pd 掺杂的石墨氮化碳 (gC ₃ N ₄ @Fe/Pd) 从水中去除 DOX的潜力，涉及去除性能、机制和途径。gC ₃ N ₄ @Fe/Pd 的结构表征表明，金属 Pd 簇装饰在 gC ₃ N ₄上均匀分布的铁纳米粒子（~28 nm）的表面上。gC ₃ N ₄的存在有效地缓解了铁纳米颗粒的团聚和过度生长，Fe、Pd 和 N 之间的强耦合作用显示出优异的 DOX 去除性能（k = 0.115 min ^-1），并且在不同的初始浓度（30-150 mg/L）下具有多功能性和材料剂量 (0.1–0.4 g/L)。提出了三种可能的 DOX 降解途径，其中催化糖部分消除是主要途径。重要的是，中间体表现出较低的毒性，最终降解产物被 gC ₃ N ₄ @Fe/Pd有效吸附。