COVER ILLUSTRATION Corpus callosum fiber tractography in sagittal orientation derived using constrained spherical deconvolution (CSD) modelling. CSD is an advanced diffusion MRI technique that partially overcomes limitations of the diffusion tensor model and better represents white matter microstructure. CSD models the diffusion signal in each voxel as a function of the fiber orientation distribution, which can be used to perform more accurate tractography. We identified the corpus callosum as a key sensorimotor tract involved in the early development of cerebral palsy in infants born very preterm.

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封面插图矢状方向的胼胝体纤维束成像使用约束球面解卷积 (CSD) 建模得出。CSD 是一种先进的扩散 MRI 技术，它部分克服了扩散张量模型的局限性，更好地代表了白质微结构。CSD 将每个体素中的扩散信号建模为纤维取向分布的函数，可用于执行更准确的纤维束成像。我们将胼胝体确定为参与早产婴儿脑瘫早期发展的关键感觉运动束。