Split-spectrum amplitude-decorrelation angiography (SSADA) is a noninvasive and three-dimensional angiographic technique with a microscale spatial resolution based on optical coherence tomography. The SSADA signal is known to be correlated with the blood flow velocity and the quantitative velocimetry with SSADA has been expected; however, the signal properties of SSADA are not completely understood due to lack of comprehensive investigations of parameters related to SSADA signals. In this study, phantom experiments were performed to comprehensively investigate the relation of SSADA signals with flow velocities, time separations, particle concentrations, signal-to-noise ratios, beam spot sizes, and viscosities, and revealed that SSADA signals reflect the spatial commonality within a coherence volume between adjacent A-scans.

中文翻译：

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用于基于定量光学相干断层扫描测速的分谱幅度去相关血管造影的信号特性

分谱振幅去相关血管造影 (SSADA) 是一种基于光学相干断层扫描的具有微尺度空间分辨率的无创三维血管造影技术。已知 SSADA 信号与血流速度相关，并且预期使用 SSADA 进行定量测速；然而，由于缺乏对与 SSADA 信号相关的参数的全面调查，SSADA 的信号特性尚未完全了解。在这项研究中，进行了体模实验以综合研究 SSADA 信号与流速、时间间隔、粒子浓度、信噪比、束斑大小和粘度的关系，并揭示 SSADA 信号反映了内部的空间共性。相邻 A 扫描之间的相干体积。