An approach to the vicinal oxyazidation of alkenes has been achieved under mild and transition metal-free conditions. This method utilizes NaN₃ as the azidation agent and 2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate (TEMPO⁺BF₄⁻) as the single-electron oxidant as well as the oxygen source. By using this protocol, various β-aminooxy azides were synthesized and several complex bioactive molecules were functionalized.

中文翻译：

---

氧铵盐介导的烯烃与 NaN3 的邻位氧叠氮化：获得 β-氨基氧叠氮化物

在温和且无过渡金属的条件下实现了烯烃邻位氧叠氮化的方法。该方法利用NaN ₃作为叠氮化剂和2,2,6,6-四甲基哌啶-1-氧代四氟硼酸铵（TEMPO ⁺ BF ₄ ^-）作为单电子氧化剂和氧源。通过使用该协议,合成了各种β-氨基氧叠氮化物, 并对几种复杂的生物活性分子进行了功能化。