Purpose

The relationship between height and incident atrial fibrillation (AF) has recently been demonstrated. We aimed to evaluate the impact of height on outcomes of ablation in patients with drug-refractory symptomatic paroxysmal AF (PAF).

Methods

A total of 689 patients (470 males; age, 53.0 ± 11.7 years) with symptomatic paroxysmal AF receiving index catheter ablation (CA) between 2003 and 2013 were enrolled in this study. The baseline characteristics, ablation, and follow-up results were evaluated. The patients were categorized according to the quartiles of height for each sex.

Results

Patients in the lower quartiles of height had a lower incidence of AF recurrence (log-rank p = 0.022). Height in female patients was strongly associated with AF recurrence (p = 0.027) after an index ablation in the 6.33 ± 4.32 years of follow-up. Female patients > 159 cm in height had a higher likelihood of AF recurrence after index CA (HR = 2.01, 95% CI: 1.24–3.25, p = 0.005) than that in those below this height. In computed tomography (CT) scan, the superoinferior diameter of the left atrium (LA) correlated with body height in females, but not in male patients.

Conclusions

Height is associated with AF recurrence after the index CA of PAF in female patients. In Asian populations, women above height 159 cm are twice as likely to have AF recurrence post-ablation as shorter women.

中文翻译：

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身高对阵发性房颤导管消融术后复发的影响

目的

最近已经证明了身高与心房颤动 (AF) 之间的关系。我们旨在评估身高对药物难治性症状性阵发性房颤 (PAF) 患者消融结果的影响。

方法

共有 689 名患者（470 名男性；年龄 53.0 ± 11.7 岁）在 2003 年至 2013 年间接受指数导管消融 (CA) 的症状性阵发性 AF 患者参加了本研究。评估基线特征、消融和随访结果。根据每个性别的身高四分位数对患者进行分类。

结果

身高较低四分位数的患者房颤复发率较低（对数秩p  = 0.022）。 在 6.33 ± 4.32 年的随访中，女性患者的身高与指数消融后的 AF 复发密切相关（p = 0.027）。身高 > 159 cm 的女性患者在指数 CA 后发生 AF 复发的可能性更高（HR = 2.01, 95% CI: 1.24-3.25, p  = 0.005）比低于该身高的患者。在计算机断层扫描 (CT) 扫描中，左心房 (LA) 的上下径与女性的身高相关，但与男性患者的身高无关。

结论

女性患者 PAF 指数 CA 后，身高与 AF 复发相关。在亚洲人群中，身高 159 厘米以上的女性在消融后发生 AF 复发的可能性是身材矮小的女性的两倍。