Sarcopenia is an aged-related syndrome that is progressive and can be accelerated by other concomitant disease states. Sarcopenia, characterized by loss of skeletal muscle mass, reduced muscle strength, and/or reduced physical performance, is one of the main reasons for limitation of daily activities in the elderly. It is associated with an increased incidence of many adverse events, such as dysfunction, falls, weakness, hospitalization, disability and even death. Sarcopenia justifies one of the most widely accepted theories that low-grade chronic inflammation associated with aging, known as inflammatory aging, is important to the pathogenesis of many age-related diseases. Currently, the diagnosis of sarcopenia is based on a comprehensive assessment of three aspects: muscle mass, muscle strength and physical performance. The measurement of muscle mass is complicated, as the measurement of muscle strength and gait speed is easily affected by the physical conditions of the subjects. This makes the measurements inaccurate and prospective, and it is difficult to achieve continuous, purposeful monitoring. In addition, serum levels of inflammatory cytokines change as inflammatory states develop in the elderly population. This manuscript focuses on the correlation between serum inflammatory cytokines and sarcopenia in recent years, plus the possible underlying mechanisms.

肌肉减少症是一种与老年相关的综合征，它是进行性的，并且可以由其他伴随疾病状态加速。肌肉减少症的特征是骨骼肌质量下降、肌肉力量下降和/或身体机能下降，是老年人日常活动受限的主要原因之一。它与许多不良事件的发生率增加有关，例如功能障碍、跌倒、虚弱、住院、残疾甚至死亡。肌肉减少症证明了最广泛接受的理论之一，即与衰老相关的低度慢性炎症，即炎症性衰老，对许多与年龄相关的疾病的发病机制很重要。目前，肌肉减少症的诊断基于三个方面的综合评估：肌肉质量、肌肉力量和身体机能。肌肉质量的测量很复杂，因为肌肉力量和步速的测量容易受到受试者身体状况的影响。这使得测量不准确和具有前瞻性，并且难以实现连续的、有目的的监测。此外，随着老年人群炎症状态的发展，炎症细胞因子的血清水平会发生变化。这份手稿的重点是近年来血清炎症细胞因子与肌肉减少症之间的相关性，以及可能的潜在机制。随着老年人群炎症状态的发展，炎症细胞因子的血清水平会发生变化。这份手稿的重点是近年来血清炎症细胞因子与肌肉减少症之间的相关性，以及可能的潜在机制。随着老年人群炎症状态的发展，炎症细胞因子的血清水平会发生变化。这份手稿的重点是近年来血清炎症细胞因子与肌肉减少症之间的相关性，以及可能的潜在机制。