The already reported, yet hazardous, Et₃N-catalyzed levoglucosenone (LGO) hydration into 1,6-anhydro-3-deoxy-β-D-erythro-hexo-pyranose-2-ulose (LGO-OH) has been greened up by substituting Et₃N with K₃PO₄ and performing the reaction in H₂O. Optimal reaction conditions (K₃PO₄ (0.05 eq.), [LGO] = 0.08 M, 5 h) not only allowed higher yields, but also limited the homocoupling of LGO, a competitive side reaction. A comparative – yet non-comprehensive and perfectible – Life Cycle Assessment (LCA) using the CML 2002 method highlighted the specific impacts where this revisited synthesis outperformed the Et₃N-catalyzed one. 1,6-Anhydro-3-deoxy-β-D-erythro-hexo-pyranose-2-ulose was then subjected to a one-pot catalyst- and organic solvent-free Baeyer-Villiger oxidation/rearrangement, without the need to perform acidic hydrolysis, to access 2-deoxy-D-ribonolactone (HO-HBO, 79% yield). To assess the potential of HO-HBO as monomer for the production of novel bio-based polyesters, the latter was finally polymerized in the presence of aliphatic diacyl chlorides to make a proof-of-concept. Resulting polyesters exhibited promising glass transition temperature (T_g) values between −21 and −2 °C and melting temperatures (T_m) from 87 to 144 °C, demonstrating the potential of HO-HBO for the production of sustainable alternatives to current fossil fuel-based polymers.

已报导，但危险，等₃的N-催化levoglucosenone（LGO）进水合1,6-脱水-3-脱氧β - D-赤-hexo吡喃糖基-2-酮糖（LGO-OH）已被绿化了通过用 K ₃ PO ₄取代 Et ₃ N并在 H ₂ O 中进行反应。最佳反应条件（K ₃ PO ₄ (0.05 eq.), [ LGO ] = 0.08 M, 5 h）不仅允许更高的产率，而且也限制了LGO的同质耦合，竞争性副反应。使用 CML 2002 方法进行的比较但不全面且可完善的生命周期评估 (LCA) 强调了这种重新审视的合成优于 Et ₃ N 催化合成的具体影响。1,6-脱水-3-脱氧β-D-赤-hexo吡喃糖基-2-酮糖然后进行一锅负载催化剂和不含有机溶剂的拜尔-维利格氧化/重排，而无需执行需要酸性水解，得到2-脱氧-D-核糖内酯（HO-HBO，产率79%）。评估HO-HBO的潜力作为生产新型生物基聚酯的单体，后者最终在脂肪族二酰氯的存在下聚合以进行概念验证。所得聚酯表现出有前途的玻璃化转变温度（Ť_克）之间的值-21和-2℃和熔化温度（Ť_米）从87至144℃，这表明的电位HO-HBO用于生产可持续替代的当前化石燃料基聚合物。