Biotransformations face the challenge of transforming industrial by-products into high added value ingredients for the cosmetic, food, and pharma industry. Phenolic acids are interesting molecules present in several agro-industrial by-products and a nice example of how enzymatic technology can transform them into high-value products. Nonetheless, most of the used enzymes are labile and need to be immobilized to achieve robust heterogeneous biocatalysts for the intensification of sustainable processes. Through heterogeneous biocatalysts using these economical and available raw materials, modified hydrophilic–lipophilic balance phenolics acids derivatives or interesting aromas and flavors can be obtained, turning environmental risks into business opportunities. In this review, we give an outlook of the most recent state of the art in this topic, which may allow giving a step toward a circular economy.

生物转化面临着将工业副产品转化为化妆品、食品和制药行业的高附加值成分的挑战。酚酸是几种农业工业副产品中存在的有趣分子，是酶促技术如何将它们转化为高价值产品的一个很好的例子。尽管如此，大多数使用的酶都是不稳定的，需要固定化以实现强大的异质生物催化剂，以加强可持续过程。通过使用这些经济且可用的原材料的异质生物催化剂，可以获得改性的亲水亲油平衡酚酸衍生物或有趣的香气和风味，将环境风险转化为商机。在这篇评论中，我们对该主题的最新技术水平进行了展望，