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Lipid Metabolism
Cold Spring Harbor Perspectives in Biology ( IF 6.9 ) Pub Date : 2021-09-01 , DOI: 10.1101/cshperspect.a040576
Navdeep S Chandel 1
Affiliation  

Fat gets a bad rap because it is implicated as the major culprit behind the obesity pandemic worldwide. The so-called fast-food diet that the United States has exported worldwide is blamed for the increase in body mass index (BMI), which is associated with health risks. Recent studies have emphasized that where you carry the fat matters in terms of health risks. For example, people carrying excess fat in the abdomen have higher risks of cancer and cardiovascular disease. It is clear that the biology of fat is complex. Fat, which is synonymous with lipids, plays an important role in our cells to maintain homeostasis. Lipids generate ATP and are involved in the synthesis of vitamins, hormones, bile salts, eicosanoids, and cellular membranes, as well as the regulation of cellular signaling. Cholesterol and phospholipids are essential components of membranes within the cell. The anabolism and catabolism of lipids is compartmentalized. Anabolism …

中文翻译:

脂质代谢

脂肪的名声很差,因为它被认为是全球肥胖流行的罪魁祸首。美国向全世界出口的所谓快餐饮食被指责导致体重指数(BMI)增加,而这与健康风险有关。最近的研究强调,脂肪携带的位置对健康风险很重要。例如,腹部脂肪过多的人患癌症和心血管疾病的风险较高。很明显,脂肪的生物学是复杂的。脂肪与脂质同义,在我们的细胞维持体内平衡中发挥着重要作用。脂质产生 ATP,并参与维生素、激素、胆汁盐、类二十烷酸和细胞膜的合成以及细胞信号传导的调节。胆固醇和磷脂是细胞内膜的重要组成部分。脂质的合成代谢和分解代谢是分开的。合成代谢...
更新日期:2021-09-01
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