Lifespan is modulated at distinct levels by multiple factors, including genetic backgrounds, the environment, behavior traits, metabolic status, and more interestingly, sensory perceptions. However, the effects of social perception between individuals living in the same space remain less clear. Here, we used the Drosophila model to study the influences of social perception on the lifespan of aged fruit flies. We found the lifespan of aged Drosophila is markedly prolonged after being co-housed with young adults of the same gender. Moreover, the changes of lifespan were affected by several experimental contexts: (1) the ratios of aged and young adults co-housed, (2) the chronological ages of two populations, and (3) the integrity of sensory modalities. Together, we hypothesize the chemical/physical stimuli derived from the interacting young adults are capable of interfering with the physiology and behavior of aged flies, ultimately leading to the alteration of lifespan.

寿命受多种因素的不同程度的调节，包括遗传背景、环境、行为特征、代谢状态，更有趣的是，感官知觉。然而，生活在同一空间的个人之间的社会感知的影响仍然不太清楚。在这里，我们使用果蝇模型来研究社会感知对老年果蝇寿命的影响。我们发现了老年果蝇的寿命与同性别的年轻人共同居住后，时间显着延长。此外，寿命的变化受到几个实验环境的影响：（1）共同居住的老年人和年轻人的比例，（2）两个人群的实际年龄，以及（3）感觉方式的完整性。总之，我们假设来自相互作用的年轻成年人的化学/物理刺激能够干扰老年苍蝇的生理和行为，最终导致寿命的改变。