Editor's Note: Dual Targeting of Wild-Type and Mutant p53 by Small-molecule RITA Results in the Inhibition of N-Myc and Key Survival Oncogenes and Kills Neuroblastoma Cells In Vivo and In Vitro,Clinical Cancer Research

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Editor's Note: Dual Targeting of Wild-Type and Mutant p53 by Small-molecule RITA Results in the Inhibition of N-Myc and Key Survival Oncogenes and Kills Neuroblastoma Cells In Vivo and In Vitro
Clinical Cancer Research ( IF 11.5 ) Pub Date : 2021-09-01 , DOI: 10.1158/1078-0432.ccr-21-2435
Mikhail Burmakin , Yao Shi , Elisabeth Hedström , Per Kogner , Galina Selivanova

The editors are publishing this note to alert readers to a concern about [this article][1] ([1][2]): in Fig. 3D, the p21 and Noxa Western blots for SKN-DZ were accidentally duplicated as the PUMA and Noxa Western blots for SKN-BE(2). The SKN-DZ blots were correct, and the authors have additional SKN

中文翻译：

编者按：小分子 RITA 对野生型和突变型 p53 的双重靶向导致 N-Myc 和关键存活癌基因的抑制，并在体内和体外杀死神经母细胞瘤细胞

编辑发布此注释是为了提醒读者关注 [这篇文章][1] ([1][2])：在图 3D 中，SKN-DZ 的 p21 和 Noxa 蛋白质印迹被意外复制为 PUMA SKN-BE(2) 的 Noxa 蛋白质印迹。SKN-DZ 印迹是正确的，作者有额外的 SKN

更新日期：2021-09-01

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