Cerium Containing Bioactive Glasses: A Review,ACS Biomaterials Science & Engineering

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Cerium Containing Bioactive Glasses: A Review
ACS Biomaterials Science & Engineering ( IF 5.4 ) Pub Date : 2021-09-01 , DOI: 10.1021/acsbiomaterials.1c00414
Alfonso Zambon ₁ , Gianluca Malavasi ₁ , Annalisa Pallini ₁ , Francesca Fraulini ₁ , Gigliola Lusvardi ₁

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Bioactive glasses (BGs) for biomedical applications are doped with therapeutic inorganic ions (TIIs) in order to improve their performance and reduce the side effects related to the surgical implant. Recent literature in the field shows a rekindled interest toward rare earth elements, in particular cerium, and their catalytic properties. Cerium-doped bioactive glasses (Ce-BGs) differ in compositions, synthetic methods, features, and in vitro assessment. This review provides an overview on the recent development of Ce-BGs for biomedical applications and on the evaluation of their bioactivity, cytocompatibility, antibacterial, antioxidant, and osteogenic and angiogenic properties as a function of their composition and physicochemical parameters.

中文翻译：

含铈生物活性玻璃：综述

用于生物医学应用的生物活性玻璃 (BG) 掺杂有治疗性无机离子 (TII)，以提高其性能并减少与手术植入物相关的副作用。该领域的最新文献显示出人们对稀土元素（尤其是铈）及其催化特性的兴趣重新燃起。掺铈生物活性玻璃 (Ce-BG) 在成分、合成方法、特征和体外评估方面有所不同。本综述概述了用于生物医学应用的 Ce-BGs 的最新发展，以及对其生物活性、细胞相容性、抗菌、抗氧化、成骨和血管生成特性的评估，作为其组成和物理化学参数的函数。

更新日期：2021-09-13

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