Perinatal maternal depressive symptoms and risk of behavioral problems at five years,Pediatric Research

当前位置： X-MOL 学术 › Pediatr. Res. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Perinatal maternal depressive symptoms and risk of behavioral problems at five years
Pediatric Research ( IF 3.1 ) Pub Date : 2021-08-31 , DOI: 10.1038/s41390-021-01719-9
Maoka Yamada ₁ , Keiko Tanaka _{1,

2} , Masashi Arakawa ₃ , Yoshihiro Miyake _{1,

2}

Affiliation

Background

Evidence on the association between perinatal maternal depression and children’s behavioral development is limited. We investigated the association between maternal depressive symptoms during pregnancy and postpartum and the risk of childhood behavioral problems using data from a birth cohort study.

Methods

Study subjects were 1199 mother–child pairs. Maternal depressive symptoms were assessed with the Center for Epidemiologic Studies Depression Scale during pregnancy and the Edinburgh Postnatal Depression Scale at 4 months postpartum. Children’s behavioral development at 5 years of age was assessed with the Strengths and Difficulties Questionnaire.

Results

Compared with children whose mothers did not experience depressive symptoms during pregnancy, those whose mothers did experience depressive symptoms during pregnancy had increased risk of emotional symptoms, conduct problems, hyperactivity, peer problems, and low prosocial behavior. Maternal depressive symptoms at around 4 months postpartum were associated with increased risk of childhood emotional problems. Compared with children whose mothers did not experience depressive symptoms during the perinatal period, those whose mothers did experience depressive symptoms both during pregnancy and postpartum had a fivefold increased risk of childhood emotional symptoms and a threefold increased risk of peer problems.

Conclusions

Our findings suggest that perinatal maternal depression is associated with behavioral problems in children.

Impact

Several epidemiological studies in Western countries have examined the association between perinatal maternal depression and children’s behavioral development, yet the results are conflicting and inconclusive.
There is limited evidence on this topic in Asia.
In our study using data from a prospective pregnancy birth cohort, maternal depressive symptoms around 4 months postpartum were associated with an increased risk of emotional symptoms in children aged 5 years.
Children whose mothers had exhibited depressive symptoms both during pregnancy and postpartum had a fivefold increased risk of childhood emotional symptoms and a threefold increased risk of peer problems.

中文翻译：

围产期产妇抑郁症状和五年时行为问题的风险

背景

关于围产期产妇抑郁与儿童行为发展之间关联的证据有限。我们使用出生队列研究的数据调查了孕期和产后产妇抑郁症状与儿童行为问题风险之间的关联。

方法

研究对象是 1199 对母子。在怀孕期间使用流行病学研究中心抑郁量表和产后 4 个月的爱丁堡产后抑郁量表评估产妇抑郁症状。使用优势和困难问卷评估儿童 5 岁时的行为发展。

结果

与母亲在怀孕期间没有出现抑郁症状的孩子相比，母亲在怀孕期间出现抑郁症状的孩子出现情绪症状、行为问题、多动、同伴问题和低亲社会行为的风险增加。产后 4 个月左右的产妇抑郁症状与儿童情绪问题的风险增加有关。与母亲在围产期没有出现抑郁症状的孩子相比，母亲在怀孕期间和产后出现抑郁症状的孩子出现儿童情绪症状的风险增加了 5 倍，出现同伴问题的风险增加了 3 倍。