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Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors
Acta Pharmaceutica Sinica B ( IF 14.7 ) Pub Date : 2021-08-31 , DOI: 10.1016/j.apsb.2021.08.027 Shenghua Gao 1 , Tianguang Huang 1 , Letian Song 1 , Shujing Xu 1 , Yusen Cheng 1 , Srinivasulu Cherukupalli 1 , Dongwei Kang 1, 2 , Tong Zhao 1 , Lin Sun 1 , Jian Zhang 1 , Peng Zhan 1, 2 , Xinyong Liu 1, 2
中文翻译:
开发有效 SARS-CoV-2 抑制剂的药物化学策略
更新日期:2021-08-31
Acta Pharmaceutica Sinica B ( IF 14.7 ) Pub Date : 2021-08-31 , DOI: 10.1016/j.apsb.2021.08.027 Shenghua Gao 1 , Tianguang Huang 1 , Letian Song 1 , Shujing Xu 1 , Yusen Cheng 1 , Srinivasulu Cherukupalli 1 , Dongwei Kang 1, 2 , Tong Zhao 1 , Lin Sun 1 , Jian Zhang 1 , Peng Zhan 1, 2 , Xinyong Liu 1, 2
Affiliation
Novel therapies are urgently needed to improve global treatment of SARS-CoV-2 infection. Herein, we briefly provide a concise report on the medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors with representative examples in different strategies from the medicinal chemistry perspective.
中文翻译:
开发有效 SARS-CoV-2 抑制剂的药物化学策略
迫切需要新的疗法来改善全球对 SARS-CoV-2 感染的治疗。在此,我们简要报告了开发有效 SARS-CoV-2 抑制剂的药物化学策略,并从药物化学的角度提供了不同策略的代表性实例。