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Neuroprotective potential of extracts from leaves of ora-pro-nobis (Pereskia aculeata) recovered by clean compressed fluids
The Journal of Supercritical Fluids ( IF 3.4 ) Pub Date : 2021-08-30 , DOI: 10.1016/j.supflu.2021.105390
Talyta Mayara Silva Torres 1 , Gerardo Álvarez-Rivera 2 , Simone Mazzutti 3 , Jose David Sánchez-Martínez 2 , Alejandro Cifuentes 2 , Elena Ibáñez 2 , Sandra Regina Salvador Ferreira 1
Affiliation  

Ora-pro-nobis (Pereskia aculeata), an emerging unconventional food plant belonging to the Cactaceae family, is known as a source of protein with high nutritional value, traditionally used in folk medicine. In this study, different compressed fluid technologies were used to obtain antioxidant rich extracts from P. aculeata leaves. The recovered extracts from ora-pro-nobis leaves showed, in general, high antioxidant potential in DPPH and FRAP in vitro assays. Complementary, supercritical fluid extracts presented acetylcholinesterase inhibition and anti-inflammatory activity. Overall, 11 compounds were identified from the non-polar extracts belonging to terpenoids and phenolic compounds. Metabolites like 2,4-Ditert-butylphenol, β-sitosterol, campesterol, phytol, Vitamin E were already identified in other Pereskia sp. extracts, but compounds like fucosterol and lupeol were also tentatively identified in the present study. Terpenes and phenolic compounds are known for its biological activities, which shows the potentiality of the P. aculeata leaves extracts recovery by compressed fluids technologies.



中文翻译:

通过清洁的压缩流体回收的 ora-pro-nobis (Pereskia aculeata) 叶子提取物的神经保护潜力

Ora-pro-nobis ( Pereskia aculeata ) 是一种新兴的非常规食用植物,属于仙人掌科,被称为具有高营养价值的蛋白质来源,传统上用于民间医学。在这项研究中,使用不同的压缩流体技术从P. aculeata 中获得富含抗氧化剂的提取物树叶。从 ora-pro-nobis 叶子中回收的提取物通常在 DPPH 和 FRAP 体外测定中显示出高抗氧化潜力。互补的超临界流体提取物表现出乙酰胆碱酯酶抑制和抗炎活性。总的来说,从属于萜类化合物和酚类化合物的非极性提取物中鉴定出 11 种化合物。2,4-二叔丁基苯酚、β-谷甾醇、菜油甾醇、植醇、维生素 E 等代谢物已在其他Pereskia sp. 中鉴定。提取物,但在本研究中也初步鉴定了岩藻甾醇和羽扇豆醇等化合物。萜烯和酚类化合物以其生物活性而著称,这显示了通过压缩流体技术回收针叶松叶提取物的潜力。

更新日期:2021-09-04
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