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Natural surfactants assisted an efficient synthesis of tetrahydro-β-carbolines
Results in Chemistry ( IF 2.5 ) Pub Date : 2021-08-31 , DOI: 10.1016/j.rechem.2021.100183
Somnath S. Gholap 1, 2 , Vinod R. Kadu 2
Affiliation  

An expeditious protocol for the synthesis of structurally diversified β-carboline derivatives has been reported using a readily available natural surfactant medium. The synthesis of β-carboline derivatives in good yields under optimized conditions was carried out by the reaction of tryptamine with aldehydes in an aqueous extract of Acacia Concinna pods. The use of an aqueous medium, ease of purification, good yield and cost-effective reaction suggest for bulk scale production β-carboline derivatives.



中文翻译:

天然表面活性剂有助于高效合成四氢-β-咔啉

已经报道了使用现成的天然表面活性剂介质合成结构多样化的 β-咔啉衍生物的快速方案。通过色胺与Acacia Concinna pods水提取物中的醛反应,在优化条件下以良好的产率合成 β-咔啉衍生物。水性介质的使用、易于纯化、良好的产率和成本效益高的反应建议用于批量生产 β-咔啉衍生物。

更新日期:2021-09-06
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