In this paper, a novel porous polyetheretherketone-hydroxyapatite (P-PEEK-HA) composite is designed and fabricated by powder mixing-heat press-alkali cleaning method. FTIR and XRD are employed to determine the component and molecular structure of the P-PEEK-HA composite. The porous layer morphology is evaluated using mercury intrusion porosimetry. FTIR and XRD suggest that there are no new crystalline phase formations during the fabrication process and no change in the crystal structure of the PEEK and HA. Mercury intrusion porosimetry shows that the pore size range is mainly 250.64–16.68 μm, and macro-meso pores larger than 5 nm are also existed. And excitedly, the open porosity of P-PEEK-HA reaches 34.115 ± 1.953%, while its closed-cell porosity is only 0.368 ± 0.022%. The pores can provide connected reticular structure for body fluid transmission and bone cells ingrowth, and HA can improve bioactivity for osseointegration. This work provides valuable basic data for the orthopedic application of P-PEEK-HA composite material, showing its excellent potential in medical engineering.

本文采用粉末混合-热压-碱洗法设计并制备了一种新型多孔聚醚醚酮-羟基磷灰石（P-PEEK-HA）复合材料。FTIR 和 XRD 用于确定 P-PEEK-HA 复合材料的成分和分子结构。使用压汞法评估多孔层形态孔隙度测定法。FTIR 和 XRD 表明在制造过程中没有新的晶相形成，PEEK 和 HA 的晶体结构没有变化。压汞孔隙率测定表明，孔径范围主要为 250.64-16.68 μm，也存在大于 5 nm 的大孔。令人兴奋的是，P-PEEK-HA 的开放孔隙率达到 34.115±1.953%，而其闭孔孔隙率仅为 0.368±0.022%。孔可以为体液传输和骨细胞向内生长提供连接的网状结构，HA可以提高骨整合的生物活性。该工作为P-PEEK-HA复合材料的骨科应用提供了宝贵的基础数据，显示了其在医学工程中的卓越潜力。