Directly accessible 8-substituted tetrahydroquinolines undergo 1,5-hydride-shift-triggered cyclization to provide difficult to access julolidine derivatives in yields of 21–98% under scandium(III) triflate catalysis. Additionally, the scope of the reaction, several follow-up transformations and a remarkable side process discovered during optimization of the conditions are highlighted.

中文翻译：

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1,5-氢化物移位触发环化反应合成不对称聚环内酯

可直接获得的 8-取代四氢喹啉在三氟甲磺酸钪 (III) 催化下经过 1,5-氢化物位移触发的环化反应，以 21-98% 的产率提供难以获得的 julolide 衍生物。此外，还强调了反应范围、几个后续转化和在优化条件期间发现的显着副过程。