Catalytic C‒H functionalization has become a powerful strategy in organic synthesis due to the improved atom-, step- and resource economy in comparison with cross-coupling or classical organic functional group transformations. Despite the significant advances in the metal-catalyzed C‒H activations, recent developments in the field of metallaphotoredox catalysis enabled C‒H functionalizations with unique reaction pathways under mild reaction conditions. Given the relative earth-abundance and cost-effective nature, nickel catalysts for photoredox C‒H functionalization have received significant attention. In this review, we highlight the developments in the field of photoredox nickel-catalyzed C‒H functionalization reactions with a range of applications until summer 2021.

中文翻译：

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镍催化 C-H 官能化中的光氧化还原催化


与交叉偶联或经典有机官能团转化相比，催化 C-H 官能化已成为有机合成中的一种强大策略，因为它具有改进的原子经济性、步骤经济性和资源经济性。尽管金属催化的 C-H 活化取得了重大进展，但金属光氧化还原催化领域的最新发展使得 C-H 官能化在温和的反应条件下具有独特的反应途径。鉴于相对丰富的地球资源和成本效益，用于光氧化还原 C-H 功能化的镍催化剂受到了极大的关注。在这篇综述中，我们重点介绍了光氧化还原镍催化 C-H 官能化反应领域的进展以及截至 2021 年夏季的一系列应用。