We aimed to compare the genetic diversity existing in VTEC O157:H7 strains isolated from cases of human disease from Argentina and Chile. For it, 76 strains were studied in relation to the distribution of genes encoding virulence factors and subtyped by lineage-specific polymorphisms (LSPA-6), and phylogroups assignment. Our results show the almost exclusive circulation of VTEC O157:H7 isolates belonging to lineage I/II, associated with hypervirulent strains, and to the phylogroup E and, on the other hand, genetic diversity present among Argentinean and Chilean strains analyzed, mainly in relation to putative virulence determinants and nle profiles.

我们旨在比较从阿根廷和智利的人类疾病病例中分离出的 VTEC O157:H7 菌株中存在的遗传多样性。为此，研究了 76 个菌株与编码毒力因子的基因分布相关，并通过谱系特异性多态性 (LSPA-6) 和系统群分配进行亚型分析。我们的研究结果表明，属于 I/II 谱系的 VTEC O157:H7 分离株几乎完全循环，与高毒性菌株相关，与系统群 E 相关，另一方面，分析的阿根廷和智利菌株之间存在的遗传多样性，主要与推定的毒力决定因素和nle配置文件。