Serodiscordant couples serves as potential source of Human Immunodeficiency Virus (HIV) transmission. Understanding demographic dynamics of serodiscordant couples plays an important role in tailoring interventions towards eliminating HIV. We conducted this cross sectional analysis in 314 Integrated Counseling and Testing Centres (ICTCs) in West Bengal, India during April 2016 to March 2020. General individuals who were detected as HIV reactive and whose spouses were also tested for HIV comprised the study population (8740 couples). Sociodemographic variables were compared across concordant and discordant arms and also between male positive (M+ F-) and female positive (F+ M-) subgroups of serodiscordant. Among the couples studied, 35.2% (95% CI: 34.2- 36.2 %) were serodiscordant. Among serodiscordant couples, the proportion of M+ F- (86.1%) was significantly higher than F+ M- (13.9%). We observed higher mean ages of couples, higher education, business & service occupations and urban residence as significantly associated with serodiscordance relationship (p < 0.05). Higher mean age of couple and lower proportion of housewives were associated with F+M- subgroup. As around 35% serodiscordant couples carry the risk of transmission to negative spouses particularly in higher age and urban residence, thus reorientation of HIV programme may be required accordingly to avert transmission in future.

血清不一致的夫妇是人类免疫缺陷病毒 (HIV) 传播的潜在来源。了解血清不一致夫妇的人口动态对于制定消除艾滋病毒的干预措施具有重要作用。2016 年 4 月至 2020 年 3 月，我们在印度西孟加拉邦的 314 个综合咨询和检测中心 (ICTC) 进行了这项横断面分析。被检测为 HIV 反应性且其配偶也接受了 HIV 检测的一般个人构成了研究人群 (8740夫妇）。比较了一致和不一致组之间的社会人口统计学变量，以及血清不一致的男性阳性 (M+ F-) 和女性阳性 (F+ M-) 亚组之间的社会人口统计学变量。在研究的夫妻中，35.2% (95% CI: 34.2- 36.2 %) 是血清不一致。在血清不一致的夫妇中，M+ F- (86. 1%) 明显高于 F+ M- (13.9%)。我们观察到较高的夫妻平均年龄、高等教育、商业和服务职业以及城市居住与血清不一致关系显着相关（p < 0.05）。较高的夫妻平均年龄和较低的家庭主妇比例与 F+M- 亚组相关。由于大约 35% 的血清不一致的夫妇有传播给阴性配偶的风险，特别是在较高年龄和城市居民中，因此可能需要相应地调整 HIV 计划以防止未来传播。较高的夫妻平均年龄和较低的家庭主妇比例与 F+M- 亚组相关。由于大约 35% 的血清不一致的夫妇有传播给阴性配偶的风险，特别是在较高年龄和城市居民中，因此可能需要相应地调整 HIV 计划以防止未来传播。较高的夫妻平均年龄和较低的家庭主妇比例与 F+M- 亚组相关。由于大约 35% 的血清不一致的夫妇有传播给阴性配偶的风险，特别是在较高年龄和城市居民中，因此可能需要相应地调整 HIV 计划以防止未来传播。